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High-Purity Recombinant Cynomolgus Monkey SIRP alpha/CD172a Protein, His Tag

Protein

High-Purity Recombinant Cynomolgus Monkey SIRP alpha/CD172a Protein, His Tag

  • Catalog number: ALP64510
  • Host species: Cynomolgus Monkey
  • Purity: >90%-95% as determined by SDS-PAGE
  • Expression System: HEK293 Cells

Recombinant Cynomolgus Monkey CD172a Protein, His Tag is produced in HEK293 Cells and the target gene encoding Glu31-Arg369 is expressed with a 6His tag at the C-terminus. The recombinant Cynomolgus Monkey CD172a protein can be used in various research applications, including cell signaling studies, immunomodulation assays, and antibody screening.

Alpha Lifetech is proud to offer recombinant protein product, Recombinant Cynomolgus Monkey CD172a Protein, to meet the needs of customers. Our recombinant CD172a protein retains the authentic structure and biological activity of native CD172a, enabling accurate and reliable functional studies. Choose Alpha Lifetech’s recombinant protein product for a reliable, effective, and cost-efficient treatment solution.

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Product Background

Signal Regulatory Protein α(SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-like cell surface receptor for CD47. SIRPα acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. SIRPα shows adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. SIRPα engagement generally produces a negative regulatory signal; it may mediate negative regulation of phagocytosis, mast cell activation and dendritic cell activation.

Product Specification

Catalog Number

ALP64510

Product Name

Recombinant Cynomolgus Monkey SIRP alpha/CD172a Protein, His Tag

Synonyms

CD172a, CD172a protein, Cynomolgus Monkey CD172a Protein, Recombinant Cynomolgus Monkey CD172a Protein, protein CD172a antibody, Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1, SHP Substrate 1, Brain Ig-Like Molecule with Tyrosine-Based Activation Motifs

Alias

CD172a, SHPS-1

Official symbol

CD172a

Species

Cynomolgus Monkey

Expression host

HEK293 Cells

Protein family

Immunoglobulin Superfamily

Size

50ug, 100ug

Purification

Affinity Purification

Purity

>90%-95% as determined by SDS-PAGE

Endotoxin

<1.0 EU/ug determined by the LAL method

Buffer

Supplied in PBS, pH7.4

Storage

For long term storage, store the reagent at -80°C. Avoid repeated freeze-thaw cycles.

Shipping Condition

Lyophilized powder is shipped at ambient temperature. Liquid form is shipped in dry ice.

Note

This product is for research use only. This product can not be used for human.

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