High-Quality Abciximab Biosimilar: (ITGA2B_ITGB3)- Research Grade

Biosimilar antibodies are highly similar to their reference products but may have slight differences due to the inherent variability of biological systems. While the amino acid sequences of biosimilar antibodies are designed to closely match those of the reference antibodies, minor differences in glycosylation patterns or post-translational modifications may exist. However, these differences are not expected to affect the overall safety or efficacy of the biosimilar.

A direct enzyme-linked immunosorbent assay (ELISA) is a type of immunoassay used to detect the presence of a specific antigen in a sample. In a direct ELISA, the antigen is immobilized or coated onto the surface of a microtiter plate well. Direct ELISA is a simple and straightforward method for the detection and quantification of specific antigens in a sample. It is commonly used in research laboratories, clinical diagnostics, and biotechnology applications.

Antibodies can be produced in mammalian cell lines such as Chinese hamster ovary (CHO) cells, NS0 cells, or human embryonic kidney (HEK) cells. Antibodies can also be expressed in bacterial hosts such as Escherichia coli (E. coli).Yeast expression systems, such as Saccharomyces cerevisiae or Pichia pastoris, are used for the production of antibodies that require eukaryotic expression but do not require complex post-translational modifications. Antibodies can also be expressed in insect cell lines such as Spodoptera frugiperda (Sf9) cells using the baculovirus expression system. Alpha Lifetech has multiple antibody expression systems for customers to choose the appropriate one.