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High-Quality Bevacizumab Biosimilar: Anti-Human VEGFA mab- Research Grade

Antibody

High-Quality Bevacizumab Biosimilar: Anti-Human VEGFA mab- Research Grade

  • Catalog number: ADT1090
  • Host species: CHO Cells
  • Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
  • Species: Human
  • Target: VEGFA [Homo sapiens]

Transcription of the VEGF protein is induced by 'hypoxia inducible factor' in a hypoxic environment. When circulating VEGF binds to VEGF receptors located on endothelial cells, various downstream effects are initiated. It should be noted that VEGF also binds to the neuropilin co-receptors , leading to enhanced signaling.

Alpha Lifetech is proud to offer biosimilar antibodies product, Bevacizumab Biosimilar, designed to revolutionize the treatment of various research conditions. Our Bevacizumab Biosimilar antibody product is manufactured using biotechnological processes, ensuring high purity, potency, and consistency in every batch. Alpha Lifetech adheres to stringent quality control measures throughout the production process, guaranteeing the safety and efficacy of our biosimilar antibody product. Choose Alpha Lifetech’s biosimilar antibody product for a reliable, effective, and cost-efficient treatment solution.

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Product Background

There are several pathways through which monoclonal antibodies (mAbs) may be cleared. Non-specific clearance of mAbs refers to target independent pinocytosis, and proteolysis of the protein into small amino acids and peptides in the reticuloendothelial system (RES) and the liver. Target-mediated clearance is a result of specific interactions between the mAb and its target antigen. Once bound, the antibody-antigen complex may be cleared via lysosomal degradation. Additionally, the production of anti-drug antibodies (ADA), which are a result of an immunogenic response to mAb-based treatment, can form complexes with mAb’s and may impact the rate of mAb clearance.

Product Specification

Catalog Number

ADT1090

Product Name

High-Quality Bevacizumab Biosimilar: Anti-Human VEGFA mab- Research Grade

Chemical Formula

C6638H10160N1720O2108S44

Tags

Bevacizumab Biosimilar, Bevacizumab, VEGFA, avastin, abatacept biosimilar, biosimilar antibodies, biosimilar monoclonal antibodies, 216974-75-3, vegfa protein, anti vegfa antibody

Host

CHO Cells

Species

Human

Clonity

Monoclonal

Target

VEGFA[Homo sapiens]

CAS Number

216974-75-3

Molecular Weigh

149.15 KDa

Alias

12-IgG1, F(ab)-12 IgG1

Isotype

IgG1 Kappa

Size

1mg, 5mg

Research area

Cancer

Application

FC, IP, ELISA, Neut, FuncS, IF, ICC

Concentration

batch dependent

Buffer

Supplied in PBS, PH7.5

Purity

>95% as determined by SDS-PAGE

Storage

Store at -20 °C for 12 months. Store at -80 °C for long term storage. Avoid repeated freezing and thawing.

Shipping Condition

Shipped on ice packs.

Note

This product is for research use only.

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