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Recombinant Human 5T4/TPBG Protein, Avi Tag, His Tag

Protein

Recombinant Human 5T4/TPBG Protein, Avi Tag, His Tag

  • Expression Host: HEK293 Cells
  • Species: Human
  • Size: 50ug,100ug,500ug
  • Official Symbol: 5T4

TPBG (Trophoblast Glycoprotein) is a Protein Coding gene. Diseases associated with TPBG include Malignant Epithelial Mesothelioma and Congenital Disorder Of Glycosylation, Type Il.May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.

Alpha Lifetech can provide Recombinant Protein products. Including various specifications such as 50, 100, and 500ug, this protein product has been purified and passed quality inspection. Scientists from all over the world are welcome to consult.

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Product Background

Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap(LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.

Product Specification

Catalog Number

ALP64514

Product Name

Recombinant Human 5T4/TPBG Protein, Avi Tag, His Tag

Alias

Human M6P1 Protein, 5T4

Alternate Names

5t4 antigen,5t4,5t4 gene,tpbg,Human 5T4 Protein,5T4 Protein,Recombinant Protein,his tag,his tag protein,avi tag,avi tag protein,tpbg protein

Official Symbol

5T4/TPBG

Species

Human

Expression Host

HEK293 Cells

Product Description

ALP64514 Recombinant Human 5T4 Protein, Avi Tag, His Tag is produced in HEK293 Cells and the target gene encoding Ser32-Ser355 is expressed with a AVI, 6His tag at the C-terminus.

Size

50ug,100ug,500ug

Purification

Affinity Purification

Purity

>90%-95% as determined by SDS-PAGE

Endotoxin

<1.0 EU/ug determined by the LAL method

Buffer

Supplied in PBS, pH7.4

Storage

For long term storage, store the reagent at -80°C. Avoid repeated freeze-thaw cycles.

Shipping Condition

Lyophilized powder is shipped at ambient temperature. Liquid form is shipped in dry ice.

Note

This product is for research use only. This product can not be used for human.

Reference

1 Starzynska, T., et al., European Journal of Cancer, 1994, DOI: 10.1016/0959-8049(94)00307-2

2 Southall, P. J., et al., British Journal of Cancer, 1990, DOI: 10.1038/bjc.1990.380

3 Gaskell, T. L., et al., Placenta, 1999, DOI: 10.1053/plac.1998.0371

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