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Recombinant Human CD150/SLAM Protein, His Tag

Protein

Recombinant Human CD150/SLAM Protein, His Tag

  • Expression Host: HEK293 Cells
  • Species: Human
  • Size: 50ug,100ug,500ug
  • Official Symbol: CD150

SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1) is a Protein Coding gene. Diseases associated with SLAMF1 include Measles and Subacute Sclerosing Panencephalitis. Among its related pathways are Toll-like receptor signaling pathway and Hematopoietic Stem Cells and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include signaling receptor activity and antigen binding. An important paralog of this gene is LY9.Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family.SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response.Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. 

 

Alpha Lifetech can provide Recombinant Protein products. Including various specifications such as 50, 100, and 500ug, this protein product has been purified and passed quality inspection. Scientists from all over the world are welcome to consult.

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Product Background

SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C(PTPN11)-dependent signal transduction operates.

Product Specification

Catalog Number

ALP64628

Product Name

Recombinant Human CD150/SLAM Protein, His Tag

Alias

Signaling Lymphocytic Activation Molecule, CD150

Alternate Names

cd150,cd150 marker,slam family,slam associated protein,slam receptor,slam seq,slam markers,Recombinant Protein,Human CD150 Protein,his tag,his tag protein

Official Symbol

CD150/SLAM

Species

Human

Expression Host

HEK293 Cells

Protein Family

SLAM Family

Product Description

ALP64628 Recombinant Human CD150 Protein, His Tag is produced in HEK293 Cells and the target gene encoding Ala21-Pro237 is expressed with a 6His tag at the C-terminus.

Size

50ug,100ug,500ug

Purification

Affinity Purification

Purity

>90%-95% as determined by SDS-PAGE

Endotoxin

<1.0 EU/ug determined by the LAL method

Buffer

20mM PB, 150mM NaCl, pH7.4

Storage

For long term storage, store the reagent at -80°C. Avoid repeated freeze-thaw cycles.

Shipping Condition

Lyophilized powder is shipped at ambient temperature. Liquid form is shipped in dry ice.

Note

This product is for research use only. This product can not be used for human.

Reference

1 Veillette, A., Dong, Z., Latour, S., Nature Reviews Immunology, 2007, DOI: 10.1038/nri1997

2 Boles, K. S., Mathew, P. A., Immunological Reviews, 2001, DOI: 10.1034/j.1600-065x.2001.1810106.x

3 Cocks, B. G., Chang, C. C., Carballido, J. M., Yssel, H., de Vries, J. E., Aversa, G., Nature, 1995, DOI: 10.1038/376260a0

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