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Recombinant Human CD160 Protein, His Tag

Protein

Recombinant Human CD160 Protein, His Tag

  • Expression Host: HEK293 Cells
  • Species: Human
  • Size: 50ug,100ug,500ug
  • Official Symbol: CD160

CD160 (CD160 Molecule) is a Protein Coding gene. Diseases associated with CD160 include Folliculitis and Kummell's Disease. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and MHC class I receptor activity.[CD160 antigen]: Receptor on immune cells capable to deliver stimulatory or inhibitory signals that regulate cell activation and differentiation.Exists as a GPI-anchored and as a transmembrane form, each likely initiating distinct signaling pathways via phosphoinositol 3-kinase in activated NK cells and via LCK and CD247/CD3 zeta chain in activated T cells.Receptor for both classical and non-classical MHC class I molecules. 

 

Alpha Lifetech specializes in producing high-quality recombinant proteins to ensure purity and activity for various research applications.

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Product Background

CD160 antigen is a Lipid-anchor that exists as a disulfide-linked homomultimer. CD160 contains one Ig-like V-type domain. The human CD160 precursor is a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain. It is weakly homologous to KIR2DL4. CD160 is expressed in the spleen, peripheral blood, and small intestine. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules.

Product Specification

Catalog Number

ALP64679

Product Name

Recombinant Human CD160 Protein, His Tag

Alias

CD160 antigen, CD160

Alternate Names

cd160,cd160 gene,Recombinant Protein,cd160 protein,his tag,his tag protein,Human CD160 Protein

Official Symbol

CD160

Species

Human

Expression Host

HEK293 Cells

Protein Family

Immunoglobulin Superfamily

Product Description

ALP64679 Recombinant Human CD160 Protein, His Tag is produced in HEK293 Cells and the target gene encoding Ile27-Ser159 is expressed with a 6His tag at the C-terminus.

Size

50ug,100ug,500ug

Purification

Affinity Purification

Purity

>90% as determined by SDS-PAGE

Endotoxin

<1.0 EU/ug determined by the LAL method

Buffer

20mM PB, 150mM NaCl, pH7.4

Storage

For long term storage, store the reagent at -80°C. Avoid repeated freeze-thaw cycles.

Shipping Condition

Lyophilized powder is shipped at ambient temperature. Liquid form is shipped in dry ice.

Note

This product is for research use only. This product can not be used for human.

Reference

1 Nguyen, T., Mitchell, T. C., Niro, J., Schaeffer, E. L., Choi, K., Journal of Immunology, 2005, DOI: 10.4049/jimmunol.174.8.4429

2 Nguyen, T., Mitchell, T. C., Niro, J., Schaeffer, E. L., Choi, K., Journal of Experimental Medicine, 2012, DOI: 10.1084/jem.20112345

3 Barak, Y., Cohen, M. H., Tsang, K. Y., Luster, A. D., Nature Immunology, 2006, DOI: 10.1038/ni1327

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