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Recombinant Human CD252/OX40L/TNFSF4 Protein, His Tag

Protein

Recombinant Human CD252/OX40L/TNFSF4 Protein, His Tag

  • Expression Host: HEK293 Cells
  • Species: Human
  • Size: 50ug,100ug,500ug
  • Official Symbol: CD252

TNFSF4 (TNF Superfamily Member 4) is a Protein Coding gene. Diseases associated with TNFSF4 include Myocardial Infarction and Systemic Lupus Erythematosus. Among its related pathways are MIF Mediated Glucocorticoid Regulation and ERK Signaling. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and tumor necrosis factor receptor binding.Cytokine that binds to TNFRSF4.Co-stimulates T-cell proliferation and cytokine production.

 

Alpha Lifetech utilizes different expression systems to produce recombinant proteins in E. coli, yeast, insect, mammalian cells, and cell-free expression systems to meet different needs.

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Product Background

Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein.OX40L is expressed on the surface of activated B cells, T cells, dendritic cells and endothelial cells. OX40L binds to OX40(CD134), a member of the TNF receptor superfamily that is expressed predominantly on activated CD4+ T cells. OX40-OX40L co-stimulates signal to promote the survival and proliferation of activated CD4+ T cells and prolong the immune response. It involved in T-cell proliferation and cytokine production. Additional, it has been found association with systemic lupus erythematosus, no association with occurrence of atherosclerosis.

Product Specification

Catalog Number

ALP64684

Product Name

Recombinant Human CD252/OX40L/TNFSF4 Protein, His Tag

Alias

Tumor necrosis factor ligand superfamily member 4, OX40L

Alternate Names

cd252,ox40l,ox40l protein,ox40l gene,tnfsf4,human tnfsf4 elisa,tnfsf4 elisa,tumor necrosis factor ligand superfamily,member 4,Human CD252 Protein,CD252 Protein,tnfsf4 Protein,Recombinant CD252 Protein,Recombinant ox40l Protein,Recombinant tnfsf4 Protein,Recombinant Protein,his tag,his tag protein

Official Symbol

CD252/OX40L/TNFSF4

Species

Human

Expression Host

HEK293 Cells

Protein Family

TNF Superfamily

Product Description

ALP64684 Recombinant Human CD252 Protein, His Tag is produced in HEK293 Cells and the target gene encoding Gln51-Leu183 is expressed with a 6His tag at the N-terminus.

Size

50ug,100ug,500ug

Purification

Affinity Purification

Purity

>90%-95% as determined by SDS-PAGE

Endotoxin

<1.0 EU/ug determined by the LAL method

Buffer

20mM PB, 150mM NaCl, pH7.4

Storage

For long term storage, store the reagent at -80°C. Avoid repeated freeze-thaw cycles.

Shipping Condition

Lyophilized powder is shipped at ambient temperature. Liquid form is shipped in dry ice.

Note

This product is for research use only. This product can not be used for human.

Protein Pathways

Cytokine-cytokine receptor interaction

Reference

1 Gough, S. C., Simmonds, M. J, Nature Reviews Rheumatology, 2010, DOI: 10.1038/nrrheum.2010.139

2 Croft, M. Nature Reviews Immunology,2009, DOI: 10.1038/nri2526

3 Bansal-Pakala, P., Halteman, B. S., Cheng, M. H., Croft, M., Journal of Immunology, 2004

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