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Recombinant Human CD30/TNFRSF8 Protein, His Tag, Avi Tag

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Recombinant Human CD30/TNFRSF8 Protein, His Tag, Avi Tag

  • Expression Host: HEK293 Cells
  • Species: Human
  • Size: 50ug,100ug,500ug
  • Official Symbol: CD30

TNFRSF8 (TNF Receptor Superfamily Member 8) is a Protein Coding gene. Diseases associated with TNFRSF8 include Peripheral T-Cell Lymphoma and Mycosis Fungoides. Among its related pathways are Akt Signaling and TNF Superfamily - Human Ligand-Receptor Interactions and their Associated Functions. Gene Ontology (GO) annotations related to this gene include transmembrane signaling receptor activity. An important paralog of this gene is TNFRSF21.Receptor for TNFSF8/CD30L.May play a role in the regulation of cellular growth and transformation of activated lymphoblasts.Regulates gene expression through activation of NF-kappa-B.  

 

Alpha Lifetech can provide Recombinant Protein products. Including various specifications such as 50, 100, and 500ug, this protein product has been purified and passed quality inspection. Scientists from all over the world are welcome to consult.

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Product Background

CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody responses. CD30 is expressed by activated, but not by resting, T and B cells. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its ligand CD30L(CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis. CD30 has been considered as a specific diagnostic biomarker of anaplastic large cell lymphoma(ALCL) and classical Hodgkin lymphoma(cHL). CD30 is also a biomarker used for targeted therapy by an antibody–drug conjugate.

Product Specification

Catalog Number

ALP64543

Product Name

Recombinant Human CD30/TNFRSF8 Protein, His Tag, Avi Tag

Alias

Tumor necrosis factor receptor superfamily member 8, CD30

Alternate Names

cd30 gene,cd30 ihc,cd30 test,cd30 protein,cd30,cd30 marker,tnfrsf8,tnfrsf8 elisa,human tnfrsf8 elisa,tnfrsf8 protein,Human CD30 Protein,Recombinant Protein,his tag,his tag protein,avi tag,avi tag protein

Official Symbol

CD30/TNFRSF8

Species

Human

Expression Host

HEK293 Cells

Protein Family

TNF Superfamily

Product Description

ALP64543 Recombinant Human CD30 Protein, His Tag, Avi Tag is produced in HEK293 Cells and the target gene encoding Phe19-Lys379 is expressed with a 6His, Avi tag at the C-terminus.

Size

50ug,100ug,500ug

Purification

Affinity Purification

Purity

>90%-95% as determined by SDS-PAGE

Endotoxin

<1.0 EU/ug determined by the LAL method

Buffer

20mM PB, 150mM NaCl, pH7.4

Storage

For long term storage, store the reagent at -80°C. Avoid repeated freeze-thaw cycles.

Shipping Condition

Lyophilized powder is shipped at ambient temperature. Liquid form is shipped in dry ice.

Note

This product is for research use only. This product can not be used for human.

Protein Pathways

Cytokine-cytokine receptor interaction

Reference

1 Falini, B., Pileri, S., Pizzolo, G., Durkop, H., Flenghi, L., & Stein, H., Blood, 1995, DOI: 10.1182/blood.V85.1.1.bloodjournal8511

2 Horie, R., & Watanabe, T., Seminars in Immunology, 1998, DOI: 10.1006/smim.1998.0116

3 Bücklein, V. L., & Ott, G., Pathobiology, 2013, DOI: 10.1159/000346300

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