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Recombinant Human CD96 Protein, Fc Tag

Protein

Recombinant Human CD96 Protein, Fc Tag

  • Expression Host: HEK293 Cells
  • Species: Human
  • Size: 50ug,100ug,500ug
  • Official Symbol: CD96

CD96 (CD96 Molecule) is a Protein Coding gene. Diseases associated with CD96 include C Syndrome and Leukemia, Acute Myeloid. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation.May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response.Promotes NK cell-target adhesion by interacting with PVR present on target cells.May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation.

Alpha Lifetech can provide Recombinant Protein products. Including various specifications such as 50, 100, and 500ug, this protein product has been purified and passed quality inspection. Scientists from all over the world are welcome to consult.

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Product Background

The cluster of differentiation(CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. The CD155 ligand CD96 is a member of the Ig superfamily. It's a immunoglobulin-like protein tentatively allocated to the repertoire of human NK receptors. NK cells recognize poliovirus receptor(PVR), anectins and nectin-like protein family member serve to mediate cell-cell adhesion, cell migration, with the presence of an additional receptor, CD96. CD96 promotes NK cell adhesion to target cells expressing PVR, stimulates cytotoxicity of activated NK cells, and mediates acquisition of PVR from target cells.

Product Specification

Catalog Number

ALP64512

Product Name

Recombinant Human CD96 Protein, Fc Tag

Alias

T-cell surface protein tactile, CD96

Alternate Names

cd96,cd96 gene,Recombinant Protein,CD96 protein,Human CD96 ,Protein,fc tag,fc tag protein

Official Symbol

CD96

Species

Human

Expression Host

HEK293 Cells

Protein Family

Immunoglobulin Superfamily

Product Description

ALP64512 Recombinant Human CD96 Protein, Fc Tag is produced in HEK293 Cells and the target gene encoding Val22-Met503 is expressed with a Fc tag at the C-terminus.

Size

50ug,100ug,500ug

Purification

Affinity Purification

Purity

>90%-95% as determined by SDS-PAGE

Endotoxin

<1.0 EU/ug determined by the LAL method

Buffer

Supplied in PBS, pH7.4

Storage

For long term storage, store the reagent at -80°C. Avoid repeated freeze-thaw cycles.

Shipping Condition

Lyophilized powder is shipped at ambient temperature. Liquid form is shipped in dry ice.

Note

This product is for research use only. This product can not be used for human.

Reference

1 Georgiev, H., Ravens, I., & Hünig, T., Trends in Immunology, 2018, DOI: 10.1016/j.it.2018.01.005

2 Dougall, W. C., Kurtulus, S., Smyth, M. J., & Anderson, A. C., Immunological Reviews, 2017, DOI: 10.1111/imr.12559

3 Wang, P. L., & Mehta, H. H., Journal of Immunology Research, 2020, DOI: 10.1155/2020/8589134

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