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Recombinant Human Galectin-9/Gal-9/Lgals9 Protein, His Tag

Protein

Recombinant Human Galectin-9/Gal-9/Lgals9 Protein, His Tag

  • Expression Host: HEK293 Cells
  • Species: Human
  • Size: 50ug,100ug,500ug
  • Official Symbol: Galectin-9

LGALS9 (Galectin 9) is a Protein Coding gene. Diseases associated with LGALS9 include Dengue Virus and Echinococcosis. Among its related pathways are Cytokine Signaling in Immune system and Interleukin-2 family signaling. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity and galactose binding. An important paralog of this gene is LGALS9B.Binds galactosides.Has high affinity for the Forssman pentasaccharide.Ligand for HAVCR2/TIM3. 

 

Alpha Lifetech specializes in producing high-quality recombinant proteins to ensure purity and activity for various research applications.

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Product Background

Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte(Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1.

Product Specification

Catalog Number

ALP64661

Product Name

Recombinant Human Galectin-9/Gal-9/Lgals9 Protein, His Tag

Alias

Galectin-9, Lgals9

Alternate Names

galectin-9,galectin-9 gene,human galectin-9 elisa,gal-9,lgals9,human lgals9 elisa,lgals9 elisa,Recombinant Protein,Human Galectin-9 Protein,galectin-9 protein,his tag,his tag protein

Official Symbol

Galectin-9/Gal-9/Lgals9

Species

Human

Expression Host

HEK293 Cells

Protein Family

Galectin Protein Family

Product Description

ALP64661 Recombinant Human Galectin-9 Protein, His Tag is produced in HEK293 Cells and the target gene encoding Met1-Thr323 is expressed with a 6His tag at the C-terminus.

Size

50ug,100ug,500ug

Purification

Affinity Purification

Purity

>90%-95% as determined by SDS-PAGE

Endotoxin

<1.0 EU/ug determined by the LAL method

Buffer

50mM MOPS, 150mM NaCl, 1mM DTT, 1mM EDTA, 5% Trehalose, pH7.4

Storage

For long term storage, store the reagent at -80°C. Avoid repeated freeze-thaw cycles.

Shipping Condition

Lyophilized powder is shipped at ambient temperature. Liquid form is shipped in dry ice.

Reference

1 Seki, M., & Hashimoto, K., Blood, 2008, DOI: 10.1182/blood-2007-11-123976

2 Tominaga, K., & Nakatsuji, Y., Current Molecular Medicine, 2007, DOI: 10.2174/156652407779940315

3 Gleason, M. K., Lenvik, T. R., McCullar, V., Felices, M., O'Brien, M. S., Cooley, S. A., ... & Miller, J. S., Blood, 2012, DOI: 10.1182/blood-2011-04-347874

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